’How exercise in old age prevents the immune system from declining

时间:2018-03-13 单词数:3570

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导读:《衰老细胞》(Aging Cell)杂志最新发布的一项研究显示,做大量运动可以有效防止人的免疫力下降,增强对感染及癌症等疾病的抵抗能力。常年运动的80岁老人的免疫系统竟可以相当于20多岁!


Doing lots of exercise in older age can prevent the immune system from declining and protect people against infections, scientists say.


They followed 125 long-distance cyclists, some now in their 80s, and found they had the immune systems of 20-year-olds.


Prof Norman Lazarus, 82, of King’s College London, who took part in and co-authored the research, said: "If exercise was a pill, everyone would be taking it.

伦敦国王学院82岁的Norman Lazarus教授参与并合作撰写了该研究报告,他说:“如果运动是一种药物,每个人都会服用。”

"It has wide-ranging benefits for the body, the mind, for our muscles and our immune system."


The research was published in the journal Aging Cell.


Prof Janet Lord, director of the Institute of Inflammation and Ageing, at the University of Birmingham, and co-author of the research, said: "The immune system declines by about 2-3% a year from our 20s, which is why older people are more susceptible to infections, conditions like rheumatoid arthritis and, potentially, cancer.

伯明翰大学炎症与衰老研究所所长兼该研究合作者Janet Lord教授说:“免疫系统从20多岁开始每年下降2-3%,这就是为什么老年人更容易感染和得病,如风湿性关节炎和潜在的癌症。

"Because the cyclists have the immune system of a 20-year-old rather than a 70- or 80-year-old, it means they have added protection against all these issues."


The researchers looked at markers in the blood for T-cells, which help the immune system respond to new infections.


These are produced in the thymus, a gland in the chest, which normally shrinks in size in adulthood.


They found that the endurance cyclists were producing the same level of T-cells as adults in their 20s, whereas a group of inactive older adults were producing very few.


The researchers believe that being physically active in old age will help people respond better to vaccines, and so be better protected against infections such as flu.


Steve Harridge, co-author and professor of physiology at King’s College London, said: "Being sedentary goes against evolution because humans are designed to be physically active.

伦敦国王学院的合着者兼生理学教授Steve Harridge说:“久坐不利于进化,因为人类就是身体活跃而设计的。”

"You don’t need to be a competitive athlete to reap the benefits - or be an endurance cyclist - anything which gets you moving and a little bit out of puff will help."


Prof Harridge and Prof Lazarus believe that highly physically active older people represent the perfect group in which to analyse the true effects of biological ageing.